NUC-like mini computers powered by AMD's Ryzen processors are available right now. OnLogic's ML100G-40 is one of them, and features the 15W Ryzen Embedded R1505G or V1605B (Radeon Vega 3 and Vega 8 Graphics respectively). Also onboard are two GbE LAN ports, M.2 storage, HDMI ports and two DisplayPort connectors. The ML100G-40 is fully configurable and available from $533.
Source: OnLogic